Coumarins and derivatives
Apexbio Technology LLC Dicoumarol 66-76-2 100mg
Dicoumarol (CAS 66-76-2) is a small molecule inhibitor targeting NAD(P)H quinone oxidoreductase 1 (NQO1) and pyruvate dehydrogenase kinase 1 (PDK1) exhibiting IC50 values of 0 37 M and 19 42 M respectively in vitro By inhibiting NQO1 Dicoumarol perturbs cellular redox homeostasis while its suppression of PDK1 modulates glycolytic flux and mitochondrial energy metabolism These actions make Dicoumarol a valuable tool for investigating tumor metabolism oxidative stress apoptosis and associated signaling pathways in biomedical research contexts
Chem-Impex International, Inc. Umbelliferone | 93-35-6 | MFCD00006878 | 100G
Umbelliferone, 93-35-6, MFCD00006878, 100G
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | MFCD00630040 | 500 MG
6-Hydroxycoumarin is a coumarin that exhibits a range of biological activities. It is intended for research use only.
- Anti-inflammatory properties
- Anti-pyretic properties
- Anti-oxidant properties
- Vasodilator properties
- Anti-amoebic properties
- Anti-bacterial properties
- Anti-fungal properties
- Bacteriostatic properties
- Antitumor properties
Medchemexpress LLC 3-Hydroxycoumarin | 939-19-5 | 99.3% | 50 MG
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase (LOX), with an IC50 for recombinant human tyrosinase (rHT) of 26 μM and an IC50 for LOX of 9.5 μM. It exhibits DPPH free radical scavenging activity and has photoprotective effects on sea urchin zygotes and embryos. The compound has also demonstrated anticancer activity against human SK-MEL-28 cells and SK-MEL3 cells in vitro.
- Inhibits tyrosinase and lipoxygenase
- Exhibits DPPH free radical scavenging activity
- Provides photoprotective effects on sea urchin zygotes and embryos
- Shows anticancer activity against human SK-MEL-28 and SK-MEL3 cells
- Can be formulated into a vesicle delivery system for topical administration
Chem-Impex International, Inc. Esculin hydrate | 531-75-9 | MFCD00149492 | 25G
Esculin hydrate, 531-75-9, MFCD00149492, 25G
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | 10 G
6-Hydroxycoumarin is a coumarin exhibiting diverse biological activities. It is noted for its anti-inflammatory, anti-pyretic, anti-oxidant, and vasodilator properties. This compound also demonstrates anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic, and antitumor activities.
- Demonstrates anti-inflammatory, anti-pyretic, and anti-oxidant activities
- Acts as a vasodilator, anti-amoebic, anti-bacterial, and anti-fungal agent
- Exhibits bacteriostatic and antitumor properties
- Appearance: light yellow to light brown solid
- Molecular formula: C9H6O3
- Molecular weight: 162.14
- Purity: 99.32%
- Melting point: 249-253 °C
- Boiling point: 248.82 °C at 760 mmHg
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 1G
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 1G
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 500MG
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 500MG
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 25 G
4-Hydroxycoumarin is an orally active coumarin derivative, and a versatile heterocyclic scaffold often used in the synthesis of various organic compounds. It possesses both electrophilic and nucleophilic properties, acting as an HIV protease inhibitor and a tyrosine kinase inhibitor. This compound also demonstrates anti-inflammatory, antibacterial, and anti-tumor effects.
- Versatile heterocyclic scaffold for organic synthesis.
- Exhibits electrophilic and nucleophilic properties.
- Acts as an HIV protease inhibitor.
- Functions as a tyrosine kinase inhibitor.
- Possesses anti-inflammatory effects.
- Demonstrates antibacterial activity.
- Shows anti-tumor effects.
- Relevant in infection research.
- Relevant in cancer research.
- High purity (99.26% by HPLC).
Medchemexpress LLC 4-Hydroxycoumarin (standard) | 1076-38-6 | 50 MG
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin, intended for research and analytical applications. It is an orally active coumarin derivative and a versatile heterocyclic scaffold, frequently used in the synthesis of diverse organic compounds. The product exhibits both electrophilic and nucleophilic properties.
- Analytical standard.
- Intended for research and analytical applications.
- Orally active coumarin derivative.
- Versatile heterocyclic scaffold.
- Used in the synthesis of various organic compounds.
- Possesses both electrophilic and nucleophilic properties.
- Functions as an HIV protease inhibitor.
- Functions as a tyrosine kinase inhibitor.
- Displays anti-inflammatory effects.
- Displays antibacterial effects.
- Displays anti-tumor effects.
Indofine Chemical 7-Hydroxycoumarin, 99%, 5 Gm
7-HYDROXYCOUMARIN 5 GM, Coumarin, Umbelliferone, C9H6O3, MW: 162.14, 99+%, 93-35-6, MFCD00006878
Sigma Aldrich Fine Chemicals Biosciences Esculin hydrate >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 10G
Esculin hydrate >=98.0% (HPLC) | Purity: >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 10G
Sigma Aldrich Fine Chemicals Biosciences Esculin hydrate >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 50G
Esculin hydrate >=98.0% (HPLC) | Purity: >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 50G
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 250 G
4-Hydroxycoumarin is an orally active coumarin derivative and a versatile heterocyclic scaffold used in the synthesis of various organic compounds. It exhibits both electrophilic and nucleophilic properties. It is identified as an HIV protease inhibitor and tyrosine kinase inhibitor, and also demonstrates anti-inflammatory, antibacterial, and anti-tumor effects.
- Acts as an HIV protease inhibitor
- Acts as a tyrosine kinase inhibitor
- Exhibits anti-inflammatory effects
- Exhibits antibacterial effects
- Exhibits anti-tumor effects
- Disrupts actin cytoskeleton in B16-F10 melanoma cells
- Reduces adhesion and motility to extracellular matrix proteins
- Inhibits tumor growth and improves survival rate in melanoma mice
- Reduces symptoms in a rat model of trinitrobenzene sulfonic acid-induced colitis